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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFAT5 All Species: 14.24
Human Site: Y932 Identified Species: 34.81
UniProt: O94916 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94916 NP_006590.1 1531 165763 Y932 N L Q Q S P V Y Q Q T S H M M
Chimpanzee Pan troglodytes XP_001168930 1803 192592 Q1205 L Q Q S P V Y Q Q T S H M M S
Rhesus Macaque Macaca mulatta XP_001093880 1771 191129 Q1173 L Q Q S P V Y Q Q T S H M M S
Dog Lupus familis XP_546854 1480 160645 P904 C E L F S S P P A V S G N E T
Cat Felis silvestris
Mouse Mus musculus Q9WV30 1225 132174 S653 F S S P S S S S H L T P E S E
Rat Rattus norvegicus NP_001100895 1548 167188 Y945 S L Q Q S P V Y Q Q P S H M M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510046 1771 190099 Y1196 N L Q Q S P V Y Q Q A S H M M
Chicken Gallus gallus XP_414226 1640 175490 Y1052 A L Q Q S P V Y Q Q A S H I M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956189 1415 152530 H843 K V L E N L Q H Q Q Q H Q R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391906 1265 132547 S693 Q Q L V S E N S R E T P Q A N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.5 85.8 91.6 N.A. 74.2 90.3 N.A. 73.2 75.3 N.A. 41.8 N.A. N.A. 22.9 N.A. N.A.
Protein Similarity: 100 84.6 86.2 94.4 N.A. 76.9 94.5 N.A. 78.4 83.1 N.A. 55.3 N.A. N.A. 37.9 N.A. N.A.
P-Site Identity: 100 20 20 6.6 N.A. 13.3 86.6 N.A. 93.3 80 N.A. 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 100 26.6 26.6 20 N.A. 13.3 93.3 N.A. 93.3 86.6 N.A. 46.6 N.A. N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 10 0 20 0 0 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 10 0 10 0 0 0 10 0 0 10 10 10 % E
% Phe: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 10 0 0 30 40 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 20 40 30 0 0 10 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 20 50 40 % M
% Asn: 20 0 0 0 10 0 10 0 0 0 0 0 10 0 10 % N
% Pro: 0 0 0 10 20 40 10 10 0 0 10 20 0 0 0 % P
% Gln: 10 30 60 40 0 0 10 20 70 50 10 0 20 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % R
% Ser: 10 10 10 20 70 20 10 20 0 0 30 40 0 10 20 % S
% Thr: 0 0 0 0 0 0 0 0 0 20 30 0 0 0 10 % T
% Val: 0 10 0 10 0 20 40 0 0 10 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 20 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _